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胃癌患者血清CEA、CA19-9和CA72-4联合检测的临床意义

丁志祥 王梅 钱高潮 赵崇晖 钱晖

江苏大学学报(医学版)2011,Vol.21Issue(6):488-491,4.
江苏大学学报(医学版)2011,Vol.21Issue(6):488-491,4.

胃癌患者血清CEA、CA19-9和CA72-4联合检测的临床意义

Clinical significance of combined detection of CEA,CA19-9 and CA72-4 in patients with gastric cancer

丁志祥 1王梅 2钱高潮 1赵崇晖 2钱晖1

作者信息

  • 1. 江苏大学基础医学与医学技术学院,江苏,镇江,212013
  • 2. 南京中医药大学附属常州中医医院检验科,江苏,常州,213003
  • 折叠

摘要

Abstract

Objective; To investigate Hie clinical value of senm CEA、 CA19-9、 CA72 -4 in patients with gastric cancer M ethods: The levels of senm CEA, CA19-9 and CA72-4 were measured in patients with gastric cancer, benign gastric diseases and nornal control by an electrochanilminescencemeihod , Hie datawere carried on statistics analysis Results; The levels of senm CEA, CA19-9 and CA72-4 in patients with gastric cancerwere significantly higher thean in benign gastric disease patients and nornal control, the difference was statistically significant P < 0. 01). The levels of senm CEA, CA19-9 and CA72-4 showed no significant difference anong different differentiation groups of gastric cancer( P > 0. 05 ), and beiween lynph node metastasis group and non-metastasis group(P >0.05). ROC cuive were applied in analysis of CEA, CA19-9 and CA72-4 in gastric cancer, the area under tie cuive were 0. 694 ± 0. 051,0. 651 ±0.053 ,0.703 ±0.049, respectively Compared with benign gastric diseases and nornal control, the difference was statistically significant (P <0.01). C onclision: Canbined detection of the levels of senm CEA, CA19-9 and CA72-4 in patients with gastric cancer can mprove the diagnostic sensitivily, and provide useful clinical infornation on the severily and prognosis in gastric cancer.

关键词

胃癌/癌胚抗原/糖类抗原19-9/糖类抗原72-4

Key words

gastric cancer carcinoanbryonic antgen/ canbohydiate antigen 19-9/ carbohydrate antigen 72-4

分类

医药卫生

引用本文复制引用

丁志祥,王梅,钱高潮,赵崇晖,钱晖..胃癌患者血清CEA、CA19-9和CA72-4联合检测的临床意义[J].江苏大学学报(医学版),2011,21(6):488-491,4.

江苏大学学报(医学版)

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