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微生物转化在中药活性成分研究中的应用

高宁 程玉鹏 毕珊珊 李慧玲 刘莉莉 蒋倩倩 王振月

中医药信息2011,Vol.28Issue(5):18-20,3.
中医药信息2011,Vol.28Issue(5):18-20,3.

微生物转化在中药活性成分研究中的应用

Application of Microbial Transformation in the Study of Active Constituents of Chinese Medicine

高宁 1程玉鹏 1毕珊珊 2李慧玲 3刘莉莉 1蒋倩倩 1王振月1

作者信息

  • 1. 黑龙江中医药大学,黑龙江哈尔滨150040
  • 2. 哈尔滨师范大学,黑龙江哈尔滨150025
  • 3. 鹤岗市人民医院,黑龙江鹤岗154100
  • 折叠

摘要

Abstract

Biological active constituents from Chinese medicine is the substantial basis for the treatment of various diseases by Chinese materia medica ( CMM) and also one of the most important substances for the modernization of CMM. Microbial transformation is playing a very important role in Chinese medicine, and it is widely used in the synthesis of natural medicine and leading compounds for specific molecular structure of modification. The micorbial transformation can enhance the effect of medicine, reduce toxicity, adjust bioavailablity, and it is also helpful to study the mechanism of drug metabolism. This review introduces the application of microbial transformation in studying active constituents of medical plants.

关键词

中药/活性成分/微生物转化

Key words

Chinese medicine/ Active constituents/ Microbial transformation

分类

医药卫生

引用本文复制引用

高宁,程玉鹏,毕珊珊,李慧玲,刘莉莉,蒋倩倩,王振月..微生物转化在中药活性成分研究中的应用[J].中医药信息,2011,28(5):18-20,3.

基金项目

国家自然科学基金面上项目( 30970300) ( 30970300)

黑龙江省中医药管理局项目(ZHY08-W39) (ZHY08-W39)

中医药信息

OACSTPCD

1002-2406

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