昆明医学院学报2011,Vol.32Issue(8):9-12,42,5.
不同分子量壳聚糖膜的制备研究
The Preparation of Chitosans Membranes with Different Molecular Weight
摘要
Abstract
Objective Growth factors are used to accelerate osseous integrations. Usually, growth factors are destroyed easily and fixed difficultly in oral implantology area. The aim of this study was to prepare chitosans membrane with different molecular weight, and provide evidence for the application of chitosans in oral implants. Method Chitosans membranes and gelatin-chitosans membranes were prepared with chitosans with different molecular weight (3 000, 100, 000, 200, 000, 450, 000) by solvent evaporation method. Results Chitosans with all different molecular weight could be prepared to chitosans membranes. The addition of gelatin didn't affect the preparation of chitosans membranes with chitosans with high molecular weight. When preparing low molecular weight chitosan membranes, the addition of gelatin and glycerin was necessary. Conclusion The preparation of chitosans membranes is related with the molecular weight and the addition of excipients.关键词
壳聚糖/分子量/成膜Key words
Chitosan/Molecular weight/Preparation of membrane分类
医药卫生引用本文复制引用
谭春园,解保生,丁仲鹃..不同分子量壳聚糖膜的制备研究[J].昆明医学院学报,2011,32(8):9-12,42,5.基金项目
云南省自然科学基金资助项目(2006C0001R) (2006C0001R)