南京医科大学学报（自然科学版）2011，Vol.31Issue(10)：1430-1435,6.
血清超敏C-反应蛋白(hsCRP)与代谢综合征关系的研究
The relationship between high sensitivity C-reactive protein and metabolic syndrome
摘要
Abstract
Objective; To investigate the relationship between high sensitivity C-reactive protein (hsCRP) and metabolic syndrome in a general population. Methods; We randomly selected 609 subjects aged 18-74 years stratified by gender and age in Songqiao.a rural area of Jiangsu Province. A standardized questionnaire was used to collect information on medical history,smoking,alcohol intake and use of medications. Blood pressure was measured by mercury sphygmomanometer. Serum hsCRP concentration was measured using a high sensitivity Bnprosec immunonephelometric assay. Metabolic syndrome was diagnosed according to the crilerions of IDF (2004). Results; With increasing number of the metabolic syndrome components,serum hsCRP concentration of both genders was increased significantly (for men,adjusted P = 0.043;for women,adjusted P = 0.003). Logistic regression indicated that prevalence of metabolic syndrome was in proportion to increasing hsCRP levels (for total subjects,adjusted P < 0.01 ;for men,adjusted P = 0.002; for women,adjusted P = 0.001). In further partial correlation analysis,waist and serum triglycerides were found to be associated with hsCRP in total subjects and both genders,while systolic blood pressure and serum HDL cholesterol were related to hsCRP only in men. Conclusion; hsCRP was independently associated with both prevalence and individual components of metabolic syndrome in this study population.关键词
超敏C-反应蛋白/代谢综合征/自然人群Key words
high sensitivity C-reactive protein/metabolic syndrome/general population分类
医药卫生引用本文复制引用
仇永亮,朱桢燕,张海锋,姚文明,徐芳,龚磊,李新立..血清超敏C-反应蛋白(hsCRP)与代谢综合征关系的研究[J].南京医科大学学报（自然科学版）,2011,31(10):1430-1435,6.基金项目
基金项目“十一五”国家科技支撑计划资助(2007BAI07A10,2008BAI65B09) （2007BAI07A10,2008BAI65B09）
江苏省科技厅社会发展计划(BE2009613) （BE2009613）
