实用医学杂志2011，Vol.27Issue(20)：3675-3677,3.DOI:10.3969/j.issn.1006-5725.2011.20.022
脂蛋白(a)和同型半胱氨酸在诊断及鉴别脑卒中的应用
Application of lipoprotein (a) and homocysteine in the diagnosis and differential diagnosis of stroke
摘要
Abstract
Objective To investigate the levels of lipoprotein ( a) [ LP ( a) ] and homocysteine ( Hey) in patients with stroke, and to evaluate the value of them in the diagnosis and differential diagnosis of stroke. Methods Serum levels of LP(a) and Hey were detected in patients with ischaemic or hemorrhagic stroke. ROC was used to evaluate the roles of LP (a) and Hey in the diagnosis of stroke and the differentiation of ischaemic stroke and hemorrhagic stroke. Results Serum levels of LP(a) and Hey were up-regulated significantly in patients with stroke than those in controls. The AUCs of LP(a) and Hey for diagnosis of stroke were 0.854 and 0.893, respectively; and those for differential diagnosis of ischaemic stroke and hemorrhagic stroke were 0.271 and 0.400, respectively. Conclusions LP(a) and Hey were up-regulated significantly in patients with stroke, and can be used to identify stroke, but they had no prominent role in differentiating ischaemic stroke and hemorrhagic stroke.关键词
卒中/脂蛋白(a)/同型半胱氨酸Key words
Stroke/Lipoprotein ( a)/Homocysteine引用本文复制引用
叶芸,李苏亮,刘凯歌,激扬,王建军,刘佰学,郑乃青..脂蛋白(a)和同型半胱氨酸在诊断及鉴别脑卒中的应用[J].实用医学杂志,2011,27(20):3675-3677,3.基金项目
陕西省教育厅科技项目(编号:11JK0723) （编号:11JK0723）
