实用医学杂志2011，Vol.27Issue(20)：3653-3655,3.DOI:10.3969/j.issn.1006-5725.2011.20.013
雄性大鼠发育期生精小管NOS和P450的表达及意义
The expression and significance of the NOS and cytochrome P450 in the sexual-maturity SD rat's aeminiferous tubule
摘要
Abstract
Objective To explore the expression and significance of the endothelial nitric oxide synthase (NOS) and cytochrome P450 (aromatase) in the sexual-maturity male SD rat's seminiferous tubule. Methods Each 6 male SD rats born for 5 weeks, 7 weeks and 10 weeks were selected. Paraffin sections of the left testis were made and the expression of the eNOS, iNOS, nNOS and P450 in the testis of male SD rat were observed with immunohistochemical ABC method. Results eNOS and P450 were expressed in the spermatocytes of the seminiferous tubule, and the positive degree were (+++), (+) and (+) respectively in the 5-w, 7-w and 10-w groups. nNOS were weak expressed in the spermatocytes of the seminiferous tubule in the 5-w groups, and were negative in 7-w and 10-w groups. iNOS were negative in spermatocytes of the seminiferous tubule in all the groups. Conclusion With the development process of sexual maturation, the expression of eNOS and P450 may be related in the spermatocytes of sexual-maturity male SD rat that mainly involved in the development of spermatocytes.关键词
一氧化氮合酶/细胞色素P450/生精小管/SD大鼠Key words
eNOS/Cytochrome P450 (aromatase)/SD rat/Seminiferous tubule引用本文复制引用
任亚萍,廖卒,孙莉,农林琳,陈筠,熊彬,邵晓云..雄性大鼠发育期生精小管NOS和P450的表达及意义[J].实用医学杂志,2011,27(20):3653-3655,3.基金项目
2010年度广西教育厅科研立项项目(编号:桂教科研2010-10) （编号:桂教科研2010-10）
