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补益营卫对衰老小鼠皮肤组织tPA表达的影响

周小平 马艳红 傅延龄

中国美容医学2011,Vol.20Issue(7):1108-1110,3.
中国美容医学2011,Vol.20Issue(7):1108-1110,3.

补益营卫对衰老小鼠皮肤组织tPA表达的影响

Effect of supplenting Ying-wei on tPA in the skin tissue of aging mice

周小平 1马艳红 2傅延龄2

作者信息

  • 1. 宁夏医科大学中医学院,宁夏银川750004
  • 2. 北京中医药大学,北京100029
  • 折叠

摘要

Abstract

Objective Discuss the deep mechanism of supplementing Ying-wei against skin aging according to the influence of supplementing Ying -wei to aging skin. Methods The mice were given subcutaneouly injections daily with the dose of D-galactose 120mg/(kg*d) in the skin. Using immuneohistochemical methods and image analysis system to evaluate the expression of tissue type plasminogen activator (tPA) in aging skin. Results After the model.tPA expression level increased significantly.and compared with the other groups there are statistically significant(P<0.01).The tPA levels in the supplementing Ying-wei groups increased.and compared with the model group there are statistically significant (P<0.01),but there was no significant difference in high.middle and low dose groups (P>0.05). Conclusion Supplementing Ying-wei can delay skin aging. Supplementing Ying-wei improved ageing skin condition by reduced the tPA aimproved breed.

关键词

皮肤衰老;营卫;免疫组织化学;组织型纤溶酶原激活物;中医药疗法

Key words

skin aging/ying-wei/immunohistochemistry/ tPA/TCM therapy

分类

生物科学

引用本文复制引用

周小平,马艳红,傅延龄..补益营卫对衰老小鼠皮肤组织tPA表达的影响 [J].中国美容医学,2011,20(7):1108-1110,3.

中国美容医学

1008-6455

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