中国内镜杂志2011，Vol.17Issue(5)：495-498,4.
靶控输注依托咪酯与异丙酚在肠镜检查中的应用
Application of etomidate or propofol given by target controlled infusion in colonoscopy sedation
汪世高 1万行荣 1张艳琴 1李荆钟 1肖志强 1周锟1
作者信息
- 1. 湖北省荆门市石化医院麻醉科,湖北荆门448000
- 折叠
摘要
Abstract
[Objective] To investigate the analgesic efficacy and safety of etomidate or propofol given by target controlled Infusion (TCI) in colonoscopy sedation. [Methods] 90 outpatients scheduled to undergo colonoscopy were randomly divided into three groups (n =30): Patients in group E received fentanyl (1 μg/kg) then etomidate given by TCI targeting effect-site (0.3 μg/mL); Patients in group P received fentanyl (1 Jig/kg) then propofol given by TCI targeting effect-site (3 μg/mL); No preventive measure were taken in the control group. The HR, ECG, SpCs, MAP in three groups were continuously monitored during the study. Pain grades, time to reach cecum,adverse reaction and patients satisfaction were recorded. [ Results ] The pain score of patients in group E and P were significantly lower than those in group C (P <0.05). The time to reach cecum was shorter in group E and P than in group C (P <0.05). The MAP value of group P patients was significantly decreased during operation (P <0.05). Patients satisfaction was better in group E and P than in group C (P <0.05). [Conclusion] Etomidate and propofol given by target controlled infusion can provide adequate sedation and analgesia in colonoscopy, and etomidate given by TCI may be more suitable for colonoscopy sedation in regard to hemodynamics.关键词
依托咪酯/异丙酚/靶控输注/肠镜Key words
etomidate/ propofol/ target controlled infusion/ colonoscopy分类
医药卫生引用本文复制引用
汪世高,万行荣,张艳琴,李荆钟,肖志强,周锟..靶控输注依托咪酯与异丙酚在肠镜检查中的应用[J].中国内镜杂志,2011,17(5):495-498,4.
