中国美容医学2011，Vol.20Issue(8)：1242-1244,3.
聚羟基丁酸酯可吸收缝线灭菌方法的实验研究
Effect of different sterilization techniques on degradation and mechanical properties of Polyhydroxybutyrate absorbable suture
摘要
Abstract
Objective To elucidate the effect of different sterilization methods on degradation and mechanical properties of absorbable suture made of Polyhydroxybutyrate (PHB). Methods The absorbable suture made of PHB were sterilized by ethylene oxide, ultraviolet exposure,75% alcohol respectively.Then.use the bacteria cultures to detect sterilization effect, Observe the degradability of suture by viscosity determination of polymer molecular weight, suture mechanical properties is determined by tensile test. Results ?Positive bacterial cultivation was noted for 10% of the sutures which were sterilized with the alcohol, and negative bacterial cultivation was noted for the other two groups. @ The reduction of the suture's viscosity after ultraviolet exposure and sterilized with the alcohol was significantly than not sterilized ;and the other group resulted not significantly. ?The alcohol and ultraviolet exposure resulted in significantdecline of breaking tenacity. Suture sterilized with ethylene oxide almost maintained normal breaking tenacity, the ultraviolet exposure suture resulted in significant decline of elongation at break, alcohol and ethylene oxide almost maintained normal breaking tenacity. Conclusion The result suggest that among the 3 different sterilization methods, the sutures which were sterilized by ethylene oxide have less influence on degradation and mechanical properties.so it may a better method of sterilization for the absorbable suture made of PHB.关键词
可吸收缝线；聚羟基丁酸酯；灭菌；降解；力学特性Key words
absorbable suture/ polyhydroxybutyrate/ sterilization/ degradation/ mechanical properties引用本文复制引用
伍锦华,艾玉峰,韩悦,杨清芳,董兆麟..聚羟基丁酸酯可吸收缝线灭菌方法的实验研究[J].中国美容医学,2011,20(8):1242-1244,3.基金项目
陕西省科学技术研究发展计划项目(编号：2008K 11-02) （编号：2008K 11-02）
