南方医科大学学报2011，Vol.31Issue(11)：1819-1823,5.DOI:44-1627/R.20111104.0931.002
吡格列酮对缺氧复氧心肌细胞损伤的保护作用及对蛋白激酶C表达的影响
Effect of pioglitazone on hypoxia/reoxygenation injury and protein kinase C expression in neonatal rat cardiomyocytes
摘要
Abstract
Objective To investigate the feasibility of vibration test in evaluation of spinal stability after instrument fixation of thoracolumbar burst fracture in pigs. Methods Twenty-one porcine spines (T11 to L5) were impacted longitudinally with different energy levels to simulate thoracolumbar burst fracture. The fractures were fixed by Luque, Harrington, Steffee and Kaneda techniques, and the anterior-posterior, lateral and vertical spinal stability was analyzed using vibration test. Results In the mild injury group, vibration test showed that only the first order frequency showed marked anterior shift in the vertical direction (P<0.05) but the main frequency did not, suggesting loosening between the vertebrae. In moderate- or high-energy impact groups, the main frequency markedly shifted forward in the vertical and anterior-posterior directions (P<0.05 or P<0.01), and obvious lateral shift was observed only in high-energy impact group. Conclusion The dynamical characteristics of the spine indicate that the main frequency markedly shift after instrument fixation (except for Luque) of thoracolumbar burst fracture, suggesting the feasibility of vibration test for evaluating spinal injury severity and instrument fixation.关键词
过氧化物酶体增殖物激活型受体γ/缺血再灌注损伤/缺血预适应Key words
thoracolumbar vertebrae/ fracture/ vibration test/ stability分类
医药卫生引用本文复制引用
朱启伟,王浩,张令尧,叶平,骆雷鸣..吡格列酮对缺氧复氧心肌细胞损伤的保护作用及对蛋白激酶C表达的影响[J].南方医科大学学报,2011,31(11):1819-1823,5.基金项目
国家自然科学基金(30872713) （30872713）
北京市自然科学基金(7082083) （7082083）
