摘要
Abstract
BACKGROUND: Balanced acupuncture treatment for the disease has a significant effect, but lack of modern scientific theoriesrelate to the mechanism.OBJECTIVE: To investigate the central mechanism of balancing technique acupuncture by using resting-state functional magneticresonance imaging (fMRI).METHODS: Ten healthy volunteers and 10 backleg pain patients with lumbar disc protrusion were examined by fMRI before andafter balancing technique acupuncture. The encephalic regions which remarkably related to bilateral amygdala were analyzed byAFNI software, and the differences in brain functional connectivity of healthy volunteers and the lumbar disc protrusion patientswere investigated after balancing acupuncture.RESULTS AND CONCLUSION: After balancing acupuncture treatment, the pain of 10 lumbar disc protrusion patients has beenimproved. The brain region of increased functional connectivity included thalamus, brain stem, ventral anterior nucleus, ventrallateral nucleus, medial frontal gyrus, superior frontal gyrus, frontal supraorbital gyrus, inferior frontal gyrus, superior temporal gyrus,middle temporal gyrus, hippocampus, cingulate gyrus and insula. Bilateral middle temporal gyrus,supraorbital gyrus,head ofcaudate nucleus, insula and left dorsal thalamus,bilateral superior frontal gyrus,left middle frontal gyrus, anterior cingulate gyrusand right inferior parietal lobule of the healthy volunteers cenhanced their connection with amygdala after balancing acupuncture.And bilateral dentate body of cerebellum, vermis, left cerebellum slope, bilateral lingual gyrus, left middle occipital gyrus, rightsuperior frontal gyrus, right precentral gyrus, bilateral inferior parietal lobule, right superior parietal lobule, and right postcentralgyrus decreased their connection with amygdale. The research on amygdale through resting state fMRI is helpful to deeplycomprehend the central mechanism of balancing technique acupuncture on backleg pain.关键词
平衡针/腰腿痛/静息态脑功能成像/脑功能连接/杏仁核/中枢机制分类
医药卫生
