实用肝脏病杂志2011，Vol.14Issue(6)：412-414,3.DOI:10.3969/j.issn.1672-5069.2011.06.005
慢性乙型肝炎患者凝血功能和血小板参数检测结果分析
The coagulation function and platelet's parameters in patients with chronic hepatitis B
占国清 1谭华炳 1李儒贵 1张薇薇 1胡波1
作者信息
- 1. 442000,湖北省十堰市,湖北医药学院附属人民医院肝病研究所
- 折叠
摘要
Abstract
Objective To explore the change and clinical significance of coagulation function index and platelet's parameters in patients with chronic hepatitis B.Methods 42 severe chronic hepatitis; 24 acute-on - chronic liver failure; 35 chronic liver failure; 32 liver cirrhosis and 50 healthy peoples as control were collected. Their coagulation function index (PT, APTT,TT, Fig) and platelet's parameters (PLT, MPV,PDW,P-LCR) were detected.Results Compared with healthy group, MPV > PDW, P-LCR increased and PLT descended in various types of chronic hepatitis groups (P＜0.0l);MPV,PDW, P-LCR were higher and PLT were lower in acute-on-chronic liver failure; chronic liver failure and liver cirrhosis groups than severe chronic hepatitis group (P＜0.0l);PLT,MPV,PDW in acute-on-chronic liver failure group and MPV in chronic liver failure group were higher than those in liver cirrhosis group (P＜0.05,P＜0.0l);There was significant difference in PLT between acute-on-chronic liver failure and chronic liver failure groups (P＜0.0l);PT, APTT>TT were higher and Fig were lower in acute-on-chronic liver failre; chronic liver failure and liver cirrhosis groups than severe chronic hepatitis group (P＜0.0l);Fig were lower in acute-on-chronic liver failure and chronic liver failure groups and APTT was higher in chronic liver failure group than those in liver cirrhosis group (P＜0.01).There was significant difference in APTT between acute-on-chronic liver failure and chronic liver failure groups (P＜0.01).Conclusion Coagulation and platelet parameters can reflect the degree of liver damage and bleeding tendency in patients with chronic hepatitis B.关键词
慢性乙型肝炎/凝血功能/血小板参数Key words
Chronic hepatitis B/Coagulation function/Platelet parameter引用本文复制引用
占国清,谭华炳,李儒贵,张薇薇,胡波..慢性乙型肝炎患者凝血功能和血小板参数检测结果分析[J].实用肝脏病杂志,2011,14(6):412-414,3.
