实用肝脏病杂志2011,Vol.14Issue(6):420-421,426,3.DOI:10.3969/j.issn.1672-5069.2011.06.008
基因1型慢性丙型肝炎初治患者获得持续病毒学应答的相关因素研究
Factors of sustained virologic response in de novo patiants with chronic hepatitis C genotype 1
肖非 1马科 1黄加权1
作者信息
- 1. 430030,武汉市,华中科技大学同济医学院附属同济医院感染病科
- 折叠
摘要
Abstract
LAbstractJ Objective To study the related factors of a sustained virofogic response in patients with chronic hepatitis C genotype 1.Method A total of 73 de novo chronic hepatitis C genotype 1 patients received combination therapy of peginterferon alpha and ribavirin for 24 to 48 weeks and were followed -up for 24 weeks.Results 47.9% of patient achieved an early viral response and 38.4% of patients got an sustained viral response;Statistical analysis indicated that patients with lower baseline HCV load (<8xlO5 IU/ml) , lower body mass index and early viral response would achieve sustained viral response (SVR) .Conclusion Baseline HCV load; BMI and early viral response are related to achieving SVR in de novo hepatitis C genotype 1 patients.关键词
慢性丙型肝炎/持续病毒学应答/基因型Key words
Hepatitis C/Sustained viral response/Genotype引用本文复制引用
肖非,马科,黄加权..基因1型慢性丙型肝炎初治患者获得持续病毒学应答的相关因素研究[J].实用肝脏病杂志,2011,14(6):420-421,426,3.