中国组织工程研究与临床康复2011，Vol.15Issue(43)：8038-8041,4.DOI:10.3969/j.issn.1673-8225.2011.43.015
人工假体置换在股骨下段骨肉瘤合并病理性骨折保肢治疗中的应用
Application of artificial total knee prosthesis replacement in limb salvage surgery for osteosarcoma with pathological fracture located in the distal femur
刘燚 1崔志明 1崔胜宇 1杨健 1严建军1
作者信息
- 1. 南通市第一人民医院骨科,江苏省南通市,226001
- 折叠
摘要
Abstract
BACKGROUND: Amputation surgery as a traditional treatment for osteosarcoma is preferred. With the continuous improvementof chemotherapy, prosthesis manufacturing process and materials science advances, it is possible to keep body functionsOBJECTIVE: To evaluate the effect of artificial total knee prosthesis replacement in the treatment of patients with osteosarcomaand pathological fracture located in the distal femur.METHODS: Limb salvage surgery with prosthetic knee replacement was performed in 9 patients with osteosarcoma andpathological fracture in the distal femur. The reconstruction of limb function was done using total knee replacement withindividualized prosthesis. Neoadjuvant chemotherapy was used in all the cases pre- and postoperaUvely.RESULTS AND CONCLUSION: The nine patients were followed up for 6-72 months Eight cases survived without tumor in 3years and 6 in 5 years. The 5 years survive rate was 66.7%. The range of extension and flexion of the knee was O°-1OO° in 6cases, and 3 in 0° 70°. The function of the knee was assessed by Enneking system. The results were graded as excellent in 6patients, good in 2 cases, and fair in 1 case. Material-related inflammation and rejection reactions were not found. It is effective forthe treatment of osteosarcoma and pathological fracture In the distal femur through extensive or radical resection andreconstruction by using prosthetic knee replacement.关键词
骨肉瘤/病理性骨折/假体置换/股骨下端/保肢分类
医药卫生引用本文复制引用
刘燚,崔志明,崔胜宇,杨健,严建军..人工假体置换在股骨下段骨肉瘤合并病理性骨折保肢治疗中的应用[J].中国组织工程研究与临床康复,2011,15(43):8038-8041,4.
