高等学校化学学报2011，Vol.32Issue(7)：1483-1487,5.
组氨酸钴氧合反应的电喷雾串联质谱
Oxygenation Reaction of Histidine Cobalt Complex by Electrospray Tandem Mass Spectrometry
摘要
Abstract
Histidine-cobalt complex is a known model compound of oxygen carriers. The investigation of its oxygenation is of great significance in revealing the reversible oxygenation mechanism of oxygen carriers. In this paper, a new method was proposed to directly investigate the oxygenation of histidine-cobalt complex by electrospray tandem mass spectrometry. The fragment ions of the oxygenated complexes were found from both ' aqueous samples of histidine-cobalt complex separately adsorbing oxygen at early time and continuously adsorbing oxygen for 24 h. The fragment ions of the oxygenated complexes were confirmed by its sub-fragment ion which just lost a neutral fragment of dioxygen by further fragmentation. Based on these results, the structure, mechanism and the species of dioxygen existed in the complex were deduced. The results show that the absorption process is a dynamic process, and the structure of the oxygenated complex changes from dinuclear superoxo-bridged complex to dinuclear superoxo-hydroxo dibridge complex according to the evolution of oxygenation. ESI-MS may be an effective technique to research the oxygenation and characterize oxygenated complexes.关键词
组氨酸/钴/电喷雾串联质谱/氧合反应/氧载体Key words
Histidine/Cobalt/ESI-MS/MS/Oxygenation/Oxygen carrier分类
化学化工引用本文复制引用
符继红,李俊芳,付佩,岳凡,张旭龙,王吉德..组氨酸钴氧合反应的电喷雾串联质谱[J].高等学校化学学报,2011,32(7):1483-1487,5.基金项目
国家自然科学基金(批准号:20961010,20762009)和教育部高等学校博士学科点专项科研基金(批准号:20096501110001)资助. （批准号:20961010,20762009）
