中国实用妇科与产科杂志2011，Vol.27Issue(10)：757-760,4.
血清CA125监测卵巢上皮性癌术后复发界值探讨
Cut-off value of serum CA125 for monitoring the recurrence of epithelial ovarian carcinoma
郭娜 1彭芝兰 1楼江燕 1刘辉 1王平 1张家文 1尹如铁 1王丹青1
作者信息
- 1. 四川大学华西第二医院妇产科,四川成都,610041
- 折叠
摘要
Abstract
Objective To explore the relationship between the cut-off value of CA 125and the recurrence of epithelial o-varian carcinoma. Methods Analyze 170 postoperative patients of epithelial ovarian carcinoma retrospectively, consisting of 135 non-recurrent and 35 recurrent cases, while 105 cases of menopausal women and 65 cases of postoperative patients of gynecological malignancies except ovarian carcinoma served as control group. Cut-off values of 5, 10, 15, 20, 25, 30, and 35 kU/L were used to compare sensitivity, and specificity. Results The median value of CA125 for nonrecurrent patients was 7. 5 kU/L; 8.4 kU/L for menopausal women; 6. 9 kU/L for postoperative patients of other gynecological malignancies, whereas the* ±s was (8. 3 ±3. 6)kU/L,(9. 1 ±4. 2)kU/L, and (7. 3 ±2. 6)kU/L, respectively. . The cut-off value of 15 kU/L produced the following results; .74.3% sensitivity, 97.0% specificity. Conclusions When 15 kU/L was used as the cut-off value combined with image examination, the sensitivity increased. This result may improve the prognosis for recurrent patients because of the early detection of recurrent lesions and early retreatment.关键词
界值/CA125抗原/卵巢上皮性癌/复发/绝经期Key words
cut-off level/ CA125 antigen/ epithelial ovarian carcinoma/ recurrence/ menopause分类
医药卫生引用本文复制引用
郭娜,彭芝兰,楼江燕,刘辉,王平,张家文,尹如铁,王丹青..血清CA125监测卵巢上皮性癌术后复发界值探讨[J].中国实用妇科与产科杂志,2011,27(10):757-760,4.
