解放军医学院学报2011,Vol.32Issue(11):1142-1143,1170,3.
胃癌细胞中miRNA-204过表达的作用
Role of miR-204 over-expression in growth and apoptosis of gastric cancer cells
摘要
Abstract
Objective To observe the effect of miR-204 over-expression on growth and apoptosis of gastric cancer cells. Methods Expression of miR-204 in gastric cancer cells was detected by real time PCR and transfected into gastric cancer cells. Growth and apoptosis of gastric cancer cells were detected by MTS and flow cytometry, respectively. Results The expression level of miR-204 was low in gastric cancer cells, which was similar to that in gastric tissue. No significant change was observed in the growth and apoptosis of gastric cancer cells when miR-204 was over-expressed. Conclusion Over-expression of miR-204 has no significant effect on the growth and apoptosis of gastric cancer cells.关键词
微小RNA/过表达/细胞凋亡Key words
microRNA/over expression/apoptosis分类
医药卫生引用本文复制引用
张文辉,桂俊豪,王昌正,常青,吴本俨..胃癌细胞中miRNA-204过表达的作用[J].解放军医学院学报,2011,32(11):1142-1143,1170,3.基金项目
国家科技支撑计划项目(2009BAI86B05) (2009BAI86B05)