国际医药卫生导报2011，Vol.17Issue(20)：2536-2538,3.DOI:10.3760/cma.j.issn.1007-1245.2011.20.027
粪便隐血免疫双联法在服用小剂量肠溶阿司匹林致消化道出血中的应用研究
To investigate the application of dejecta occult blood with hemoglobin and/or transferrin monoclonal immunoassay on gastrointestinal bleeding induced by taking low-dose ASA
章金灿 1郑大明 1许贤彬 1陆卫歆 1杨燕珠 1苏锦霞1
作者信息
摘要
Abstract
Objective To explore the application value of dejecta occult blood coupled with hemoglobin and/or transferrin monoclonal immunoassay on inspect gastrointestinal bleeding induced by taking low-dose ASA.Methods 328 cases taking low-dose ASA in long-time were set as therapy group;30 cases patients with Heart-Brain vas disease not taking ASA and not having the sign of gastrointestinal bleeding were set as control group,Detected dejecta occult blood with hemoglobin and/or transferrin monoclonal immunoassay 1 week,1 month,3 months,6 months before taking medicine.Took Gastroscopy if dejecta occult blood were positive to see if upper gastrointestinal were bleeding or not.Results ① Among these 328 patients,dejecta occult blood was detected with hemoglobin and/or transferrin monoclonal immunoassay; 40 cases were positive( 12.2％ )in therapy group,while control group had 1 case(3.3％,1/30);there was statistical difference ( P ＜ 0.05 ).② There were 29 cases taking Gastroscopy of 40 cases whose dejecta occult blood was positive; 24 cases had pathology significance; hemoglobin and transferrin monoclonal immunoassay was positive of the other 5 cases.③There was no statistical significant difference on bleeding time (P＞ 0.05 ).Conclusion Dejecta occult blood detected with hemoglobin and/or transferrin monoclonal immunoassay could be a routine inspection for gastrointestinal bleeding induced by taking low-dose ASA in long-time.关键词
胃肠出血/阿司匹林/血红蛋白/转铁蛋白/胃镜检查Key words
Gastrointestinal hemorrhage/Aspirin/Hemoglobin/Transferrin/Gastroscopy引用本文复制引用
章金灿,郑大明,许贤彬,陆卫歆,杨燕珠,苏锦霞..粪便隐血免疫双联法在服用小剂量肠溶阿司匹林致消化道出血中的应用研究[J].国际医药卫生导报,2011,17(20):2536-2538,3.
