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颅脑手术后重症患者并发真菌感染临床分析

伍军 张明宇 谭泽明 陈风华 霍雷 方加胜

中国感染控制杂志2011,Vol.10Issue(5):361-363,372,4.
中国感染控制杂志2011,Vol.10Issue(5):361-363,372,4.

颅脑手术后重症患者并发真菌感染临床分析

Clinical analysis on fungal infections in severe patients after craniotomy

伍军 1张明宇 1谭泽明 1陈风华 1霍雷 1方加胜1

作者信息

  • 1. 中南大学湘雅医院,湖南长沙 410008
  • 折叠

摘要

Abstract

Objective To explore the risk factors, clinical characteristics, prevention and treatment of fungal infections in severe patients after craniotomy. Methods Clinical data of 27 severe patients with fungal infections after craniotomy in neurosurgery department in a hospital between January 2009 and June 2011 were analyzed retrospectively. Results Of 27 patients, 12 cases had lung fungal infections, 8 had urinary tract infections, 4 had gastrointestinal tract infections, 2 had surgical site infections, and 1 had bloodstream infections; 22 cases improved or cured, 1 died, 4 patients gave up treatment and were discharged. The major risk factors for fungal infections in postoperative severe patients were coma, application of broad-spectrum antimicrobial agents and glucocorticoids, and a variety of invasive treatment operatioa Conclusion The key to the prevention of nosocomial fungal infection after craniotomy is the rational use of broad-spectrum antimicrobial agents and glucocorticoids. The clinical manifestations of fungal infections are not typical. For postoperative severe patients who require long-term use of antimicrobial agents, anti-fungal agents should be used preventively; Patient who has fungal infection should choose appropriate antifungal a-gents, antifungal agents should be used early,enough and full course.

关键词

颅脑手术/真菌感染/医院感染/危险因素

Key words

craniotomy/ fungal infection/ nosocomial infection/ risk factor

分类

医药卫生

引用本文复制引用

伍军,张明宇,谭泽明,陈风华,霍雷,方加胜..颅脑手术后重症患者并发真菌感染临床分析[J].中国感染控制杂志,2011,10(5):361-363,372,4.

中国感染控制杂志

OACSTPCD

1671-9638

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