国际医药卫生导报2011，Vol.17Issue(20)：2496-2499,4.DOI:10.3760/cma.j.issn.1007-1245.2011.20.012
48例行颈部淋巴结活检术的鼻咽癌预后分析
Analysis on the prognosis 48 nasopharyngeal cancer patients taken lymph node biopsy
李坊铭 1陈国健 1张钦华 1程霞1
作者信息
- 1. 529030 江门市中心医院中山大学附属江门医院肿瘤一区
- 折叠
摘要
Abstract
Objective To explore the influence facter of neck lymph node biopsy on the prognosis for NPC.Methods 48 NPC cases taken cervica lymph node metastases were treated by radiotherapy from January,2006 to December,2006.Analyzed recurrence and 4-year survival rates.Results The rates of recurrence and distant metastasis were 14.5％ and 52.1％; and overall 4-year survival rate was 43.6％ in the 48 cases.The rate of metastasis was 73.3％ in Radiotherapy alone group(Group A),and 42.4％ in chemotherapy group(Group B)(P=0.015); and overall 4-year survival rates were 26.3％ and 55.2％,respectively in the both groups(P=0.049).The metastasis rate was 37.9％ in the patients treated within 15 days( Group C ),while 73.7％ beyond 15 days(Group D) (P=0.047); and overall 4-year survival rates were 54.5％ and 20.0％,respectively in the both groups(P=0.025); The metastase rates were 75.0％ for the dose of cervical lymph node under 64Gy(Group E),and 40.6％ for the dose above 64 Gy (Group F),P=0.025;and overall 4-year survival rates were 25.0％ and 53.1％,P=0.064.Conclusion The neck lymph node biopsy can increase the rate of distant metastasis and decrease the rate of survival for NPC,so early radiotherapy,chemotherapy,and the dose above 64Gy can improve the clinical effect of NPC.The longterm treatment result need enrolling more patients and long-term follow-up.关键词
鼻咽肿瘤/放射治疗/化疗/远处转移/淋巴结活检/预后Key words
Nasopharyngeal neoplasms/Radiotherapy/Chemotherapy/Metastasis/Lymph node biopsy/Prognosis引用本文复制引用
李坊铭,陈国健,张钦华,程霞..48例行颈部淋巴结活检术的鼻咽癌预后分析[J].国际医药卫生导报,2011,17(20):2496-2499,4.
