国际医药卫生导报2011，Vol.17Issue(22)：2718-2723,6.DOI:10.3760/cma.j.issn.1007-1245.2011.22.002
抗流感病毒药物神经氨酸酶抑制剂奥司他韦研究进展
Research progress on oseltamivir-one of influenza neuraminidase inhibitors
摘要
Abstract
The outbreak of highly pathogenic avian influenza H5N1 in Asia and the global spread of new type 2009 H1N1,implies that to design and explore new anti-influenza drugs is quite urgent.Neuraminidase(NA) plays an important role in influenza virus reproduction and dissemination,furthermore the active center of NA is highly conservative,so the research on influenza NA inhibitors has been greatly concerned.This article reviews the research progress on pharmacodynamics,pharmacokinetics and drug resistance of oseltamivir,providing advices for its future application in clinic.关键词
神经氨酸酶抑制剂/流感病毒/奥司他韦/研究进展Key words
Neuraminidase inhibitor/Influenza virus/Oseltamivir/Research progress引用本文复制引用
张玲,魏绍静..抗流感病毒药物神经氨酸酶抑制剂奥司他韦研究进展[J].国际医药卫生导报,2011,17(22):2718-2723,6.基金项目
广东省自然科学基金资助项目(8151006002000005) （8151006002000005）
