中华医学杂志（英文版）2011，Vol.124Issue(23)：3875-3878,4.DOI:10.3760/cma.j.issn.0366-6999.2011.23.008
Intervertebral disc degeneration and bone density in degenerative lumbar scoliosis: a comparative study between patients with degenerative lumbar scoliosis and patients with lumbar stenosis
Intervertebral disc degeneration and bone density in degenerative lumbar scoliosis: a comparative study between patients with degenerative lumbar scoliosis and patients with lumbar stenosis
DING Wen-yuan 1YANG Da-long 2CAO Lai-zhen 1SUN Ya-peng 1ZHANG Wei 1XU Jia-xin 1ZHANG Ying-ze 1SHEN Yong1
作者信息
- 1. Department of Spine Surgery,the Third Hospital of Hebei Medical University,Shijiazhuang, Hebei 050051, China
- 2. Orthopaedic Research Institute,the Third Hospital of Hebei Medical University,Shijiazhuang, Hebei 050051, China
- 折叠
摘要
Abstract
Background Degenerative lumbar scoliosis is common in older patients.Decreased bone density and the degeneration of intervertebral discs are considered to be correlated with degenerative lumbar scoliosis.A means of quantifying the relative signal intensity for degenerative disc disease has not been previously discussed.The purpose of this study was to compare bone mineral density and intervertebral disc degeneration between degenerative lumbar scoliosis and lumbar spinal stenosis patients in a nine-year retrospective study.Methods From January 2001 to August 2010,96 patients with degenerative lumbar scoliosis were retrospectively enrolled and 96 patients with lumbar spinal stenosis were selected as controls.Cobb angle,height of the apical disc and the contiguous disc superiorly and inferiorly on convex and concave sides,the height of the convex and concave side of the apical and the contiguous vertebral body superiorly and inferiorly were measured in the scoliosis group.The height of L2/L3,L3/L4,L4/L5 discs and the height of L2/L4 vertebral body was measured in the control group.The grade of intervertebral disc degeneration was evaluated using T2WI sagittal images in both groups.The bone density of lumbar vertebrae was measured with dual-energy X-ray.Results In scoliosis group,the intervertebral disc height on the convex side was greater than the height on the concave side (P ＜0.001 ).The vertebral body height on the convex side was greater than the height on the concave side (P=0.016).There was a significant difference between the scoliosis group and the control group (P=0.003),and between T-value and the rate of osteoporosis between the two groups (both P ＜0.001).Results were verified using multiple linear regression analysis.Conclusions Degenerative lumbar scoliosis is accompanied by height asymmetry between the intervertebral disc and vertebral body regarding the convex and concave surfaces.There is a positive correlation between the angle of scoliosis and the disc index,the degree of degeneration of the intervertebral disc,and a negative correlation between the angle of scoliosis and bone density.关键词
degenerative scoliosis/osteoporosis/intervertebral disc/lumbar/degenerationKey words
degenerative scoliosis/osteoporosis/intervertebral disc/lumbar/degeneration引用本文复制引用
DING Wen-yuan,YANG Da-long,CAO Lai-zhen,SUN Ya-peng,ZHANG Wei,XU Jia-xin,ZHANG Ying-ze,SHEN Yong..Intervertebral disc degeneration and bone density in degenerative lumbar scoliosis: a comparative study between patients with degenerative lumbar scoliosis and patients with lumbar stenosis[J].中华医学杂志（英文版）,2011,124(23):3875-3878,4.
