浙江医学2011，Vol.33Issue(11)：1617-1619,3.
肺硬化性血管瘤的临床病理及免疫表型特点分析
Histopathological characteristics and immuophenotype of pulmonary sclerosing hemangioma
魏红权 1冯晶晶 2魏树梅2
作者信息
- 1. 310012,杭州,浙江省立同德医院病理科
- 2. 浙江大学医学院附属第二医院病理科
- 折叠
摘要
Abstract
Objective To review the histopathological characteristics and immuophenotype of pulmonary sclerosing he-mangioma (PSH). Methods The histopathological examination was performed in 28 cases ofPSH and the expression of vimentin, ER, PR, TTF- 1, CK, CD34, Syn, CgA, Catetinin and Ki- 67 were detected with immunohistochemical methods. Results PSH demonstrated the histological characters with variable proportions of solid, papillary, sclerotic and hemangioma-like patterns. Cuboidal or columnar cells covered the papillary and cleft- side spaces in solid areas whereas solid areas and stalk of papillary projections were composed of uniform round or polygonal pale cells. The cuboidal or columnar cells were positive for CK, TTF- 1 and EMA. The round or polygonal pale cells expressed EMA, TTF- 1, PR and vimentin. Neither of these two type cells expressed mesothelial and vascular endothelialmarkers. Sporadic expression of Syn and CgA was observed in a few cases. Conclusion PSH is a rare lung tumor, with various histological appearance. The mixed- type is more common than other types. Immunohistochem-is try is important for diagnosis and differential diagnosis ofthis type oftumor.关键词
肺硬化性血管瘤/临床病理/免疫组化Key words
Pulmonary sclerosing hemangioma/Clinicopathology/Immunohistochemistry引用本文复制引用
魏红权,冯晶晶,魏树梅..肺硬化性血管瘤的临床病理及免疫表型特点分析[J].浙江医学,2011,33(11):1617-1619,3.
