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高胆固醇血症红细胞膜CD35、CD44s、CD59分子表达研究

张页 战祥辉 何华亮 苗会娜 戴劲

武警医学2011,Vol.22Issue(12):1026-1028,3.
武警医学2011,Vol.22Issue(12):1026-1028,3.

高胆固醇血症红细胞膜CD35、CD44s、CD59分子表达研究

Study of CD35, CD44s, and CD59 of human erythrocytes cytomembrane in hypercholesterolemia

张页 1战祥辉 1何华亮 1苗会娜 1戴劲1

作者信息

  • 1. 100037,武警北京总队第二医院急诊科
  • 折叠

摘要

Abstract

Objective To study the CD35, CD44s, CD59 molecular weight distribution of erythrocyte cytomembrane in hyper-cholesterolemia. Methods The CD35, CD44s, and CD59 molecular weight distribution in erythrocytes of 32 sub - healthy subjects with hypercholesterolemia( > 6mmol/L) was observed by flow cytometry and compared with that of control group. Results Compared with normal group, the CD35, CD44s, and CD59 average fluorescence intensity was reduced. Conclusions The reduction of CD35-,CD44s-, CD59 molecular weight distribution resulting in immune regulation functional disorder may be one of the causes of atherosclerosis.

关键词

CD35/CD44s/CD59/红细胞膜/高胆固醇血症

Key words

CD35/CD44s/CD59/erythrocytes/cytomembrane hypercholesterolemia

分类

医药卫生

引用本文复制引用

张页,战祥辉,何华亮,苗会娜,戴劲..高胆固醇血症红细胞膜CD35、CD44s、CD59分子表达研究[J].武警医学,2011,22(12):1026-1028,3.

基金项目

武警总部科研基金资助项目(WKH2003029) (WKH2003029)

武警医学

OACSTPCD

1004-3594

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