江苏大学学报（自然科学版）2011，Vol.32Issue(5)：607-611,5.DOI:10.3969/j.issn.1671-7775.2011.05.022
癌基因密码子间的距离和Y-内积表示及其应用
Application of oncogene using distance and Y-inner product between codons
摘要
Abstract
In order to study the relationship between the second-position base and hydrophobicity when the normal genes become oncogenes, the distance and Y-inner product between codons of oncogene were defined according to the algebraic structure. On GF (7) ,36 primitive polynomials and their roots were calculated to represent the corresponding biological significance. Based on above definitions, the hydrophobicity change of amino acids for several types of cancers relating to p53 gene were discussed. The results show that the distance between two codons is not smaller than 1 when normal genes become oncogenes and the second-positions of codons mutates. When the second-position base of A mutates to G or C, the Y-inner product is negative, while the Y-inner product is larger than 4 when T mutates to G,C or A.关键词
密码子/距离/Y-内积/癌基因/氨基酸/亲疏水性Key words
codon/ distance/ Y-inner product/ oncogene/ amino acids/ hydrophobicity of amino acids分类
数理科学引用本文复制引用
朱平,闰艳艳,孔娟娟..癌基因密码子间的距离和Y-内积表示及其应用[J].江苏大学学报（自然科学版）,2011,32(5):607-611,5.基金项目
江南大学创新团队发展计划项目(PIRTJiangnan2008 CXTD02) （PIRTJiangnan2008 CXTD02）
