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纳米微胶囊的制备及其药物控释放性能的研究

陶梅 陈云 胡中青

安徽医科大学学报2011,Vol.46Issue(11):1154-1156,3.
安徽医科大学学报2011,Vol.46Issue(11):1154-1156,3.

纳米微胶囊的制备及其药物控释放性能的研究

Preparation of polymeric nanocapsules and its controlled-releasing function study

陶梅 1陈云 2胡中青2

作者信息

  • 1. 安徽医科大学化学教研室,合肥,230032
  • 2. 中国科学技术大学高分子科学与工程系,合肥,230026
  • 折叠

摘要

Abstract

To prepare nanocapsules with good permeability. Methods Polystyrene ( PSt) nanocapsules with liquid core were prepared by 60Co γ- ray radiation inducing miniemulsion polymerization, in which N-vinyl pyrrolidone ( NVP ) was used as polar monomer. 1 HNMR, TEM and UV methods were used to characterize the nanocapsules. Results 1NMR method verified that during the polymerization, graft copolymerization between NVP and PSt had taken place. Conclusion Increment of the amount of the surfactant and the ratio of St to NVP are advantaged for the formation of nanocapsules with good permeability.

关键词

微胶囊/控释放/细乳液

Key words

nanocapsule/ controlled release/ miniemulsion

分类

化学化工

引用本文复制引用

陶梅,陈云,胡中青..纳米微胶囊的制备及其药物控释放性能的研究[J].安徽医科大学学报,2011,46(11):1154-1156,3.

基金项目

安徽省高校优秀青年人才基金(编号:2010SQRL076) (编号:2010SQRL076)

安徽医科大学校科研基金(编号:2008kj04) (编号:2008kj04)

安徽医科大学学报

OA北大核心CSTPCD

1000-1492

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