安徽医科大学学报2011，Vol.46Issue(11)：1175-1178,4.
汉族人3915例特应性皮炎患者的临床特征分析
The clinical features of atopic dermatitis: a study of 3 915 patients from Chinese Han population
摘要
Abstract
To study the clinical and epidemiological profiles of Chinese Han patients with atopic der-matitis( AD ). Methods Total 3 915 AD patients who met Hanifin-Rajka diagnostic criteria were enrolled in this survey. Differences of clinical and epidemiological profiles were evaluated in relation to ages of onset and gender with SPSS 10. 0. Results 3 313 ( 84. 6% ) patients started AD before 2 years old, and more males were affected in early AD group. A positive family history of atopy was seen in 2 778 patients ( 71% ). ' Pure' AD was noted in 2 267 ( 57. 9% ), and 1 648 ( 42. 1% ) suffered from a ' mixed' type. This survey indicated the prevalence rates of asthma and allergic rhinitis ( AR ) were lower in early AD ( P <0. 01 ). 84% AD patients were mild to moderate disease, males appeared to have more severe involvement than females ( P < 0. 05 ). The frequencies of 13 monor signs, which included facial erythema, orbital darkening, icthyosis/keratosis pilaris/palmer hyperlinearity were significantly different between early AD group and onset age ≥ 2 years group ( P <0. 05 ). Additionly, the frequencies of other 11 minor signs, such as early onset, icthyosis/keratosis pilaris/palmer hyperlinearity, Dennie-Morgan fold were statistical difference between males and females ( P <0. 05 ). Conclusion Differences of the severity of disease, clinical and epidemiological profiles in relation to ages of onset and gender are statistical significant, which provide clues to describe Chinese Han AD patients.关键词
特应性皮炎/流行病学/临床特征Key words
atopic dermatitis/ epidemiology/ clinical features分类
医药卫生引用本文复制引用
邵莉梅,杨森,张学军,叶文正,李珊珊,李存涛,裴小平,姜新,张丽君,陈日新,肖风丽..汉族人3915例特应性皮炎患者的临床特征分析[J].安徽医科大学学报,2011,46(11):1175-1178,4.基金项目
国家自然科学基金(编号:81071284) （编号:81071284）
