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水溶性维生素核磁共振定量分析的研究

张烨 刘小鹏 张友杰

波谱学杂志2011,Vol.28Issue(3):357-365,9.
波谱学杂志2011,Vol.28Issue(3):357-365,9.

水溶性维生素核磁共振定量分析的研究

Studies of NMR Quantitative Analysis for Water-Soluble Vitamins

张烨 1刘小鹏 2张友杰1

作者信息

  • 1. 武汉生物工程学院制药工程系,湖北武汉 430415
  • 2. 华中师范大学分析测试中心,湖北武汉 430079
  • 折叠

摘要

Abstract

NMR quantitative analysis of drug is the method with simple operation and use just a few amount of samples. The method can accomplish the qualitative as well as the quantitative analysis simultaneously, and do not need any standard compound but only the common internal standard for the quantitative analysis. The analysis speed and the precision of the method is close to the HPLC method. In this paper, the results of determination for water-soluble vitamin by NMR quantitative analysis with chemical a nalysis have been compared . The experiment shows the results of the NMR quantitative analysis are coincident with the result of the chemical method. Therefore, the NMR quantitative analysis method can be used market regulation of drugs.

关键词

核磁共振(NMR)/定量分析/水溶性维生素/中国药典

Key words

NMR, quantitative analysis, water-soluble vitamins, Chinese Pharmacopoeia

分类

数理科学

引用本文复制引用

张烨,刘小鹏,张友杰..水溶性维生素核磁共振定量分析的研究[J].波谱学杂志,2011,28(3):357-365,9.

基金项目

国家自然科学基金资助项目(21072069,20802023). (21072069,20802023)

波谱学杂志

OA北大核心CSCDCSTPCD

1000-4556

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