华东师范大学学报(自然科学版)Issue(4):61-68,8.DOI:10.3969/j.issn.1000-5641.2011.04.007
热带爪蟾胚胎对三丁基锡致畸作用响应的敏感时期
Sensitive periods of teratogenic effects of tributyltin on Xenopus tropicalis embryos
摘要
Abstract
Xenopus tropicalis embryos were exposed to 200 ng ? L-1 tributyltin chloride (TBTC1) during different periods in the experiement of three days. The percent of survival embryos decreased by 10% in the 3rd, 20% in 3 d treatment groups, respectively. The whole body length reduced by 30% in the 2nd day, 20% in the 3rd day and 39% in 3 d treatment groups, respectively. More than 90% embryos showed malformations in treatment groups. The main characteristic malformations were abnormal eyes, enlarged proctodaeum, narrow fins or absence of fins, bent tails, etc. Compared with the control, the eyes were smaller in the 2nd day and bigger in the 3rd day treatment groups, respectively. The dorsal fins were a little narrower in the 1st day treatment group, both dorsal and ventral fins were much narrower with tail-tip residue or gap near the proctodaeum in the 2nd day treatment group, and the fins were slightly narrower in the 3rd day treatment group, respectively. The results suggest that the malformations in the eyes and fins were more sensitive to different exposure periods.关键词
三丁基锡(TBT)/爪蟾/胚胎/ 致畸Key words
tributyltin (TBT)/ Xenopus tropicalis/ embryos/ teratogenesis分类
生物学引用本文复制引用
袁静,张小利,玉琳,刘俊奇,曹庆珍,施华宏..热带爪蟾胚胎对三丁基锡致畸作用响应的敏感时期[J].华东师范大学学报(自然科学版),2011,(4):61-68,8.基金项目
国家自然科学基金(20877023) (20877023)
长江水环境教育部重点实验室开放基金(YRWEF06003) (YRWEF06003)