农业环境科学学报2011，Vol.30Issue(8)：1521-1525,5.
微囊藻毒素一LR对罗非鱼肝脏活性氧自由基含量及相关抗氧化酶活性的影响
Effects of Microcystin-LR on Antioxidant Enzymes and Reactive Oxygen Species in Tilapia Fish
摘要
Abstract
This paper firstly focused on the variation of reactive oxygen species( ROS) and antioxidant enzymes, such as superoxide dismutase (SOD) and catalase(CAT), to tilapia in exposed to microcystin-LR(MC-LR) by intraperitoneal. In this experiment, five treatments (control, 50, 100, 250, 500 μg·kg-1 MC-LR) were designed, the value of ROS, SOD, CAT were detected at time 2, 12, 24, 36, 84 h. The results showed that surplus ROS were generated in liver in exposed to MC-LR by intraperitoneal. SOD and CAT played a different role in eliminating the surplus ROS, dynamic process of SOD showed that it had a sudden increase in 36 h, and dynamic process of CAT showed that it had two peaks respectively in 24 h and 84 h. The experiment was to certify that antioxidant enzymes could be used as biomarkers in monitoring the toxic effect of tilapia in exposed to MC in liver, due to their dose and time-response effect variation. The experiment makes a progress in studying the toxic mechanism of microcystin in terms of the antioxidant defence system.关键词
微囊藻毒素/罗非鱼/活性氧自由基/抗氧化酶Key words
microcystin/ tilapia/ reactive oxygen species/ antioxidant enzymes分类
资源环境引用本文复制引用
陈家长,宋超,胡庚东,瞿建宏,孟顺龙,范立民..微囊藻毒素一LR对罗非鱼肝脏活性氧自由基含量及相关抗氧化酶活性的影响[J].农业环境科学学报,2011,30(8):1521-1525,5.基金项目
现代农业产业技术体系(CARS-49) （CARS-49）
