应用化学2011，Vol.28Issue(9)：1012-1016,5.DOI:10.3724/SP.J.1095.2011.00375
硫脲壳聚糖Co(Ⅱ)配合物的制备、抑茵活性及与血清白蛋白的作用
Preparation, Antibacterial Activities of Thiourea-chitosan-Co(Ⅱ) Complex and Interaction with Bovine Serum Albumin
摘要
Abstract
Thiourea-chitosan-Co( II) complex was prepared and characterized by FT-IR, UV-Vis absorbance spectra and TG-DTA methods, the antibacterial activities of thiourea-chitosan-Co( II ) complex against E. Coli and St. Aureus were studied in vitro. Moreover, the interaction between thiourea-chitosan-Co( II ) complex and bovine serum albumin ( BSA) was also studied by ultraviolet and fluorescence spectroscopies. The results confirm that the complex is formed, and the antibacterial activities of thiourea-chitosan-Co( II ) complex is obviously enhanced comparing to its ligands and the complex can quench the intrinsic fluorescence of BSA.关键词
硫脲壳聚糖Co(Ⅱ)配合物/抑菌性能/血清白蛋白Key words
thiourea-chitosan-Co ( II) complex/ antibacterial activity/ bovine serum albumin分类
化学化工引用本文复制引用
冯小强,李小芳,杨声..硫脲壳聚糖Co(Ⅱ)配合物的制备、抑茵活性及与血清白蛋白的作用[J].应用化学,2011,28(9):1012-1016,5.基金项目
甘肃天水师范学院“青蓝”人才工程及物理无机化学重点学科基金资助项目(ZD0840) （ZD0840）
