应用化学2011，Vol.28Issue(9)：1063-1066,4.DOI:10.3724/SP.J.1095.2011.00610
激光法测定硝唑尼特结晶介稳区间
Measurement of Crystallization Metastable Zone of Nitazoxanide Using the Laser Scattering Method
赵地顺 1吕斌 2寇成 1杨洁 1董兰芬 1张妍1
作者信息
- 1. 河北科技大学 化学与制药工程学院 石家庄050018
- 2. 河北科技大学 理学院 石家庄050018
- 折叠
摘要
Abstract
The saturated and supersaturated characteristics of nitazoxanide in DMF, DMSO, methanol and acetone at different temperatures were investigated by using the laser detection technique. The crystallization metastable zone widths of nitazoxanide were obtained at different temperatures in the above four solvents. The results indicated that the solubility, supersolubility and the metastable zone width of nitazoxanide enhance with increasing temperature. At the same temperature, the metastable zone width of nitazoxanide relations as follows: acetone < DMSO < methanol < DMF.关键词
硝唑尼特/溶解度/超溶解度/介稳区宽度Key words
nitazoxanide/ solubility/ supersolubility/ metastable zone width分类
化学化工引用本文复制引用
赵地顺,吕斌,寇成,杨洁,董兰芬,张妍..激光法测定硝唑尼特结晶介稳区间[J].应用化学,2011,28(9):1063-1066,4.
