安徽农业大学学报2011，Vol.38Issue(5)：680-682,3.DOI:34-1162/s.20110829.1433.022
年龄对SAMP8小鼠不同脑区NSF含量的影响
Influence of age on the levels of NSF in different brain regions in SAMP8 mice
摘要
Abstract
The NSF(N-ethylmaleimide-sensitive fusion protein) and GAPDH (reference protein) in dorsal hippocampus, ventral hippocampus, frontal lobe, parietal lobe and olfactory bulb were detected by western blot. The relative amount of the NSF in the dorsal hippocampus, frontal lobe and parietal lobe in the 13-month-old mice was significantly higher than that in the young mice (Ps < 0.05), and the amount of NSF in the 13-month-old mice in the dorsal hippocampus was higher than that in the 9-month-old mice (P < 0.05); the relative content of NSF in the SAMP8 mice in the ventral hippocampus and olfactory bulb had no significant age-related changes (Ps >0.05). Our results suggested that during the lifetime, the amount of NSF increases with aging in some brain regions of SAMP8 mice.关键词
衰老/NSF/小鼠/免疫印迹法Key words
aging/ NSF/ mouse/ western blot分类
医药卫生引用本文复制引用
马汉,陈贵海,黄玲,李学伟,王飞,杨启纲..年龄对SAMP8小鼠不同脑区NSF含量的影响[J].安徽农业大学学报,2011,38(5):680-682,3.基金项目
国家自然科学基金项目(30872730)和安徽省自然科学基金项目(09020103001)共同资助. （30872730）
