中国临床医学影像杂志2011，Vol.22Issue(11)：774-779,6.
三阴性乳腺癌与非特异性肉芽肿性乳腺炎的影像鉴别诊断
Differential diagnosis of imaging fmdings between patients with triple-negative breast cancer and patients with idiopathic granulomatous mastitis
郝亮 1余日胜 1崔凤 2任兴昌 2徐海滨 2杜芳 2徐坤元2
作者信息
- 1. 浙江大学医学院附属二院放射科,浙江杭州310009
- 2. 杭州市中医院,浙江杭州310007
- 折叠
摘要
Abstract
Objective: To analyze the imaging findings of triple-negative breast cancer (TNBC) and to improve the understanding and diagnostic performance of the disease, by comparing it with idiopathic granulomatous mastitis (ICM). Methods: The imaging findings in 63 randomly assigned women with surgically and pathologically confirmed TNBC(n=45) and IGM(n=18) were retrospectively analyzed. All cases underwent a mammographic examination. An ultrasonic examination was performed in 37 cases of TNBC and 18 cases of IGM. MR examination was performed in 33 cases of TNBC and 14 cases of IGM. The mammographic imaging findings included lesion shape, density, margin, calcification, axillary adenopathy and thickening of the skin. The ultrasound imaging findings included shape, margin, size, echo, axillary adenopathy and thickening of the skin. The MR imaging findings included tumor shape, size, margin and internal enhancement, signal intensity within the tumor as well as peripheral signal intensity on T2-weighted, then the type of time-signal intensity curve(TIC) was analyzed. Results: The results of comparing TNBC group with IGM group showed as follows: ①Mammography imaging findings: mass type accounts for 67%(30/45) in TNBC group and 39%(7/18) in IGM group. Smooth margin of the lesion accounts for 60%(18/30) in TNBC group, while 29%(2/7) in IGM group. ②Ultrasound imaging findings: mass type accounts for 92%(34/37) in TNBC group and 89%(16/18) in IGM group. Smooth margin of the lesion accounts for 62%(21/34) in TNBC group, while 37%(6/16) in IGM group. ?MR imaging findings: mass type accounts for 91%(30/33) in TNBC group and 86%(12/14) in IGM group. Rim en-hancement accounts for 67% (20/30) in TNBC group and 75% (9/12) in IGM group. For the rim enhancement mass type, smooth margin of the lesion accounts for 70%(14/20) in TNBC group, while ll%(l/9) in IGM group; peripheral hyperintense pattern on T2-weighted accounts for 85%(17/20) in TNBC group and 21%(2/9) in IGM group. Conclusion: We believe that through careful observation of the lesion site, shape, edge of the tumor mass and peripheral signal intensity on T2-weighted, enhancement pattern and the TIC types, might be useful for the identification of TNBC and IGM.关键词
乳腺肿瘤/乳腺炎/磁共振成像/乳房X线摄影术/超声检查Key words
Breast neoplasms/ Mastitis/ Magnetic resonance imaging/ Mammography/ Ultrasonography分类
医药卫生引用本文复制引用
郝亮,余日胜,崔凤,任兴昌,徐海滨,杜芳,徐坤元..三阴性乳腺癌与非特异性肉芽肿性乳腺炎的影像鉴别诊断[J].中国临床医学影像杂志,2011,22(11):774-779,6.
