激光生物学报2011，Vol.20Issue(5)：595-599,5.DOI:10.3969/j.issn.1007-7146.2011.05.006
胃癌患者手术前后血清的激光拉曼光谱研究
A Study on Laser-Raman Spectrum of Preoperative and Postoperative Serum of Patients with Gastric Cancer
摘要
Abstract
In order to discuss the spectrum of preoperative and postoperative serum of patients with gastric cancer and its clinical applications, Laser-Raman spectra of 30 cases of cancer cell culture fluid, 20 cases of serum of healthy persons, and preoperative and postoperative serum of 41 patients with gastric cancer are detected respectively . The results indicate that the Raman spectrum of cancer cell culture fluid is distinct from that of blank culture fluid and its peak is correlated positively with its culturing time; there are significant differences between the Raman spectrum of serum of patients with gastric cancer and that of healthy people; the peak of Raman spectrum of postoperative serum of patients with gastric cancer is noticeably lower than that of preoperative serum. It can be concluded that the Raman spectrum may be an examination technique to research stomach cancer cell in vitro, and has potentialities to become a new technique to detect gastric cancer,to monitor prognostically and to evaluate the therapeutic effect.关键词
胃癌/血清/手术前后/激光拉曼光谱Key words
gastric cancer/serum/preoperative and postoperative/Laser Raman spectrum分类
医药卫生引用本文复制引用
陶家友,冷爱民,王华秀,徐代升,周菊林..胃癌患者手术前后血清的激光拉曼光谱研究[J].激光生物学报,2011,20(5):595-599,5.基金项目
湖南省教育厅项目(08C396) （08C396）
