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沙眼衣原体临床株基因分型及体外药敏试验结果分析

杨丽娜 江勇 刘全忠

山东医药2011,Vol.51Issue(39):1-3,3.
山东医药2011,Vol.51Issue(39):1-3,3.

沙眼衣原体临床株基因分型及体外药敏试验结果分析

Genotyping of Chlamydia trachomatis clinical isolates and analysis of drug sensitive test in vitro

杨丽娜 1江勇 1刘全忠2

作者信息

  • 1. 天津医科大学第二医院,天津300211
  • 2. 天津医科大学总医院
  • 折叠

摘要

Abstract

Objective To assess the genotyping distribution of Chlamydia trachomatis( Ct) clinical isolates and its susceptibility to common antimicrobial agents; to improve the treatment level of urogenitaltract infection. Methods Poly-merase chain reaction-restriction fragment length polymorphism(PCR-RFLP)was performed to determine the genotype of 52 Ct; the MICs of 9 antimicrobial agents to Ct were determined. Results There were 49 strains of E type, 2 strains of G type, and 1 strain of J type. The highest MIC of 9 antimicrobial agents to Ct was erythromycin, and the lowest was clar-ithromycin; 13 strains were found resistant. Conclusions The most prevalent genotypes of Ct infection in Tianjin is E type, which is susceptive to clarithromycin; the clinic should take attention to that Ct strains resistant to erythromycin have been found.

关键词

沙眼衣原体/基因型/药敏试验

Key words

Clamydia trachomatis/genotypes/drug sensitive test

分类

医药卫生

引用本文复制引用

杨丽娜,江勇,刘全忠..沙眼衣原体临床株基因分型及体外药敏试验结果分析[J].山东医药,2011,51(39):1-3,3.

基金项目

国家自然科学基金资助项目(30872285). (30872285)

山东医药

1002-266X

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