山东医药2011,Vol.51Issue(39):1-3,3.
沙眼衣原体临床株基因分型及体外药敏试验结果分析
Genotyping of Chlamydia trachomatis clinical isolates and analysis of drug sensitive test in vitro
摘要
Abstract
Objective To assess the genotyping distribution of Chlamydia trachomatis( Ct) clinical isolates and its susceptibility to common antimicrobial agents; to improve the treatment level of urogenitaltract infection. Methods Poly-merase chain reaction-restriction fragment length polymorphism(PCR-RFLP)was performed to determine the genotype of 52 Ct; the MICs of 9 antimicrobial agents to Ct were determined. Results There were 49 strains of E type, 2 strains of G type, and 1 strain of J type. The highest MIC of 9 antimicrobial agents to Ct was erythromycin, and the lowest was clar-ithromycin; 13 strains were found resistant. Conclusions The most prevalent genotypes of Ct infection in Tianjin is E type, which is susceptive to clarithromycin; the clinic should take attention to that Ct strains resistant to erythromycin have been found.关键词
沙眼衣原体/基因型/药敏试验Key words
Clamydia trachomatis/genotypes/drug sensitive test分类
医药卫生引用本文复制引用
杨丽娜,江勇,刘全忠..沙眼衣原体临床株基因分型及体外药敏试验结果分析[J].山东医药,2011,51(39):1-3,3.基金项目
国家自然科学基金资助项目(30872285). (30872285)