摘要
Abstract
Epigenetics is the study branch of genetic variation of apparent genetics. In recent years,with further research,epigenetics displays their invaluable role and broad prospects in human growth and development period and the idiopathic pregnant diseases and their prevention and control. In mammalian germ cells and preimplantation developmental stages,its occurs genome methylation patterns through the large-scale demethylation and then re-methylation reprogram-ming,resulting in a developmental potential cells. Environmental factors during pregnancy,including exposure to toxic hazardous substances, endocrine disruptors, as well as food, medicines can change the epigenetic model, leading to various diseases in pregnant women and their offspring.关键词
基因组印迹/DNA甲基化/胎儿生长迟缓/先兆子痫/表观遗传学Key words
Genomic imprinting/ DNA methylation/ Fetal growth retardation/Pre-eclampsia/Epigenetics
