国际妇产科学杂志2011，Vol.38Issue(5)：407-410,414,5.
多囊卵巢综合征胰岛素抵抗新进展
Molecular Mechanism and Management in Insulin Resistance in Polycystic Ovary Syndrome
摘要
Abstract
Polycystic ovary syndrome (PCOS)is one of the most common endocrine disorder with a variety of clinical manifestations among women of reproductive age. Its features include chronic anovulation, multicystic morphology of ovaries,hyperandrogenism. In recent years,insulin resistance (IR)has been regarded as one of the mechanisms of the development of PCOS,and is also associated with the hyperandrogenemia and dysfunction of ovaries. Many researches have been done on the molecular mechanism of IR in PCOS,which might provide a theory foundation for the treatment. This review thus focuses on the molecular mechanism and treatment of insulin resistance in patients with PCOS.关键词
多囊卵巢综合征/胰岛素抗药性/高胰岛素血症/葡萄糖钳制技术/二甲双胍Key words
Polycystic ovary syndrome/ Insulin resistance/ Hyperinsulinism/Glucose clamp technique/Metformin引用本文复制引用
沈文娟,匡洪影,张跃辉..多囊卵巢综合征胰岛素抵抗新进展[J].国际妇产科学杂志,2011,38(5):407-410,414,5.基金项目
国家中医药管理局2008中医药行业专项(200807021) （200807021）
科技部国家“十一五”科技支撑计划(2007BAI20B015) （2007BAI20B015）
黑龙江省杰出青年基金(JC200804) （JC200804）
