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破骨细胞前体细胞的研究进展

赵熠 蔡育

国际口腔医学杂志2011,Vol.38Issue(6):670-673,4.
国际口腔医学杂志2011,Vol.38Issue(6):670-673,4.DOI:10.3969/j.issn.1673-5749.2011.06.014

破骨细胞前体细胞的研究进展

Research progress on osteoclasts precursor cells

赵熠 1蔡育2

作者信息

  • 1. 武汉大学口腔医院修复科 武汉430079
  • 2. 武汉大学口腔医院口腔颌面外科 武汉430079
  • 折叠

摘要

Abstract

Osteoclasts precursor cells fire generated in the bone marrow from hematopoietic stem cells, and form osteoclasts in the affected sites to resorb bone. Many cytokines or growth factors could potentially induce osteoclast formation directly or indirectly from osteoclasts precursor cells to mediate bone loss. Blockade of signaling pathways in differentiation of osteoclasts precursor cells into osteoclasts may be an effective therapeutic strategy to prevent bone loss in a variety of common bone diseases. The authors reviewed the research advances about the origin and characteristics of osteoclasts precursor cells and regulation of their functions.

关键词

破骨细胞/破骨细胞前体细胞/骨吸收

Key words

osteoclast/ osteoclast precursor cell/ bone resorption

分类

生物科学

引用本文复制引用

赵熠,蔡育..破骨细胞前体细胞的研究进展[J].国际口腔医学杂志,2011,38(6):670-673,4.

国际口腔医学杂志

OACSTPCD

1673-5749

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