国际病理科学与临床杂志2011,Vol.31Issue(5):448-452,5.DOI:10.3969/j.issn.1673-2588.2011.10.017
肾小球系膜细胞与氧化应激
Glomerular mesangial cell and oxidative stress
孙文佳1
作者信息
- 1. 安徽医科大学附属省立医院内分泌科,合肥230001
- 折叠
摘要
Abstract
Mesangial cell is one of the most active natural cells in renal tissues. Many factors such as high glucose, angiotensin II, aldosterone, mechanical stress, inflammation, and lipid deposition are involved in oxidative stress of mesangial cells, which promote the occurrence and development of glomerular sclerosis including diabetic nephropathy. Thiazolidinediones, angiotensin converting enzyme inhibitors , and angiotensin-H receptor blockers, adosterone receptor blockers, statins drugs, and antioxidants can alleviate the oxidative stress of mesangial cell.关键词
肾小球硬化/糖尿病肾病/系膜细胞/氧化应激Key words
glomerular sclerosis/diabetic nephropathy/ mesangial cell/ oxidative stress引用本文复制引用
孙文佳..肾小球系膜细胞与氧化应激[J].国际病理科学与临床杂志,2011,31(5):448-452,5.