生命科学研究2011，Vol.15Issue(5)：455-459,5.
适配体传感器在微生物检测中的应用
Applications of Aptasensors in Detecting Microorganism
摘要
Abstract
Aptamers are nucleic acid sequences that can bind to a wide variety of targets from small molecules to whole cells with high affinity and specificity. They can be obtained in vitro through systematic evolution of ligands by exponential enrichment (SELEX) procedure. Aptamers present an alternative to antibodies as recognition agents in diagnostic and detection assays. Aptamer-based biosensors (aptasensors) are analysis devices, which combine biological recognition components with signal conversion element to detect targets. Providing real time, high sensitive and specific tests, aptasensor technology is one of the fast growing areas in microbial rapid detection. Advances in aptamers, SELEX procedures, aptasensors and their applications in detection of microorganism are reviewed.关键词
适配体传感器/SELEX技术/检测/微生物Key words
aptasensors/ SELEX/ detection/ microorganism分类
生物科学引用本文复制引用
文晓棠,李华,邓乐..适配体传感器在微生物检测中的应用[J].生命科学研究,2011,15(5):455-459,5.基金项目
国家自然科学基金资助项目(30770570) （30770570）
