摘要
Abstract
Objective To study the use of CT gemstone spectral imaging in the diagnosis of gastric pre-cancerous lesion and early gastric cancer. Methods Twenty-six patients (16 male and 10 female,mean age 60 years,ranged from 26-84 years) with 14 early gastric cancer,6 high grade intraepithelial neoplasia (HCIEN) and 6 low grade intraepithelial neoplasia(LGIEN) were scanned by Discovery CT75OHD Gemstone Spectral Imaging (GSI). One-way analysis of variance was performed for analyzing the resulting parameters, and P<0.05 was considered as significant. Also, two radiologists assessed the lesion with conventional imaging characteristics. Results There was a statistically significant difference between early gastric cancer and normal gastric wall tissue in 40-140keV 101 monoenergetic images: arterial phase 40keV, 50keV, 60keV, 70keV, material value based water and iodine and portal phase 40keV, 50keV, 60keV, 70keV, 80keV, effective monoenergetic spectrum value, material value based iodine. Significant differences were seen in 40-140keV 101 monoenergetic images: arterial phase 40keV, 50keV monoenergetic spectrum value between early gastric cancer and low grade intraepithelial neoplasia. No significant difference in 40 -140keV 101 monoenergetic images: material value based water and iodine was found between early gastric cancer and high grade intraepithelial neoplasia. There was no significant difference between early gastric cancer and high grade intraepithelial neoplasia, high grade intraepithelial neoplasia and low grade intraepithelial neoplasia, low grade intraepithelial neoplasia and normal gastric tissues (P>0.05). Conclusions CT Gemstone Spectral Imaging could provide additional imaging information that may improve the differentiation of gastric pre-cancerous lesion and early gastric cancer.关键词
早期胃癌/胃癌前病变/宝石能谱计算机断层扫描/鉴别诊断Key words
Early gastric cancer/ Gastric pre-cancerous lesions/ Computer tomograph Gemstone Spectral Imaging/ Differential diagnosis分类
医药卫生
