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基质金属蛋白酶-9在软骨肉瘤中的表达及临床意义

覃章柱 谭酉菊 彭春 卢璐

陕西医学杂志2011,Vol.40Issue(11):1471-1472,1476,3.
陕西医学杂志2011,Vol.40Issue(11):1471-1472,1476,3.

基质金属蛋白酶-9在软骨肉瘤中的表达及临床意义

Expression of MPP-9 protein in chondrosarcoma and its clincal significance

覃章柱 1谭酉菊 1彭春 1卢璐1

作者信息

  • 1. 广东省高州市中医院骨二科 高州525200
  • 折叠

摘要

Abstract

Objective:To investigate the MPP-9 protein expression in chondrosarcoma and its clincal Significance. Methods:Using immunohistochemistry test ( S-P methods) , We examined the expressions of MPP-9 protein in 28 cases of chondrosarcoma, 12 cases of benign cartilage tumor and 10 cases of normal cartilage as control group. Results: The expression of MPP-9 protein was 71. 43% in chondrosarcoma. The positive rate of MPP-9 in chondrosarcoma was significantly higher than that in normal cartilage tissue and cartilage tumor. Conclusion: MPP-9 protein expression is closely related to tumorigenesis of chondrosarcoma, suggesting that MPP-9 protein may serve as a valuable marker for histologic grade,malignant development and prognostic assessment of chondrosarcoma.

关键词

软骨肉瘤/免疫学/明胶酶B/分析/免疫组织化学

Key words

Chondrosarcoma/inurnunology/Gelatinase/B/analysis/Immunohistochemistry

分类

医药卫生

引用本文复制引用

覃章柱,谭酉菊,彭春,卢璐..基质金属蛋白酶-9在软骨肉瘤中的表达及临床意义[J].陕西医学杂志,2011,40(11):1471-1472,1476,3.

陕西医学杂志

OACSTPCD

1000-7377

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