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藏药川西千里光中倍半萜类成分的研究

杨爱梅 李笑颜 冯艳

中医药学报2011,Vol.39Issue(5):66-68,3.
中医药学报2011,Vol.39Issue(5):66-68,3.

藏药川西千里光中倍半萜类成分的研究

Isolation and Structural Elucidation of Eremophilenolides from Senecio Solidagineus Hand.-Mazz.

杨爱梅 1李笑颜 1冯艳1

作者信息

  • 1. 兰州理工大学生命科学与工程学院,甘肃兰州730050
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摘要

Abstract

Objective;To isolate and identify the chemical constituents from the whole plant of Senecio solidagineus Hand.- Mazz. , which has been used as traditional herb medicine in the treatment of some diseases. Methods;The compounds were isolated by column chromatography and their structures were elucidated through spectroscopic analysis ( NMR). Results; Six eremophilenolides were isolated and identified as; 1 (3,8a - dihydroxyeremophil -7(11), 9- dien - 8β, 12-olide( I), 10 -hydroxyeremophil-7(ll) -en-8,12 -olide(Ⅱ) 8 ,10 - dihydroxyeremophil-7(11)-en -8,12- olide ( Ⅲ ) , 10 - hydroxy - 8 methoxyeremophil -7(11) -en- 8,12 - olide ( IV ) , 6 - hydroxyeremophil - 7 (ll)-en-8,12 - olide( V ), 10 - hydroxyeremophil -7( 11) ,8(9) -dien-8,12 - olide ( VI). Conclusion: All compounds were isolated from Senecio solidagineus Hand. - Mazz for the first time.

关键词

千里光属/川西千里光/倍半萜/分离

Key words

Senecio/Senecio solidagineus Hand. - Mazz/Eremophilenolides/Isolation

分类

医药卫生

引用本文复制引用

杨爱梅,李笑颜,冯艳..藏药川西千里光中倍半萜类成分的研究[J].中医药学报,2011,39(5):66-68,3.

基金项目

甘肃省自然科学基金项目 ()

兰州理工大学优秀青年教师资助计划(Q200808) (Q200808)

教育部大学生创新计划 ()

中医药学报

OACSTPCD

1002-2392

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