中国病理生理杂志2011，Vol.27Issue(12)：2423-2428,6.DOI:10.3969/j.issn.1000-4718.2011.12.037
移植物抗宿主病和移植物抗白血病效应的发生机制及分离策略的研究进展
Advance in mechanisms and strategies of separation between graft-versus-host disease and graft-versus-leukemia effect
罗浩 1柯丹1
作者信息
- 1. 华中科技大学同济医学院医院,湖北,武汉,430030
- 折叠
摘要
Abstract
Graft - versus - host disease ( GVHD ) is an important factor and has significant influence on survival after allogeneic hematopoietic stem cell transplantation ( allo - HSCT ). Graft - versus - leukemia ( GVL ) effect is a key factor that affects the treatment and recurrence after allo - HSCT. In order to increase the validity and safety on allo - HSCT in clinical application, the detailed mechanisms of GVHD and GVL are investigated, and the separation of GVL from GVHD in allo - HSCT, including early prediction and diagnosis of GVHD, modification of donor graft cells and drug intervention, is extensively studied.关键词
干细胞/移植/移植物抗宿主病/移植物抗白血病效应Key words
Stem cells/ Transplantation/ Graft vs host disease/ Graft vs leukemia effect分类
医药卫生引用本文复制引用
罗浩,柯丹..移植物抗宿主病和移植物抗白血病效应的发生机制及分离策略的研究进展[J].中国病理生理杂志,2011,27(12):2423-2428,6.
