中国神经再生研究（英文版）2011，Vol.6Issue(36)：2850-2855,6.DOI:10.3969/j.issn.1673-5374.2011.36.009
Voxel-based statistical analysis of regional cerebral glucose metabolism in children with attention-deficit hyperactivity disorder
Voxel-based statistical analysis of regional cerebral glucose metabolism in children with attention-deficit hyperactivity disorder
Ji-Hoon Kim 1Young-In Chung 2Jung Sub Lee 3In-Joo Kim 2Yong-Ki Kim 4Seong-Jang Kim5
作者信息
- 1. Division of Child-Adolescent Psychiatry, Department of Psychiatry, Pusan National University School of Medicine, Yangsan-si, Gyeongnam, Republic of Korea
- 2. Medical Research Institute, Pusan National University School of Medicine, Yangsan-si, Gyeongnam, Republic of Korea
- 3. Department of Psychiatry, Pusan National University School of Medicine, Yangsan-si, Gyeongnam, Republic of Korea
- 4. Department of Orthopedic Surgery, Pusan National University School of Medicine, Yangsan-si, Gyeongnam, Republic of Korea
- 5. Medical Research Institute, Pusan National University School of Medicine, Yangsan-si, Gyeongnam, Republic of KoreaDepartment of Nuclear Medicine, Pusan National University School of Medicine, Yangsan-si, Gyeongnam, Republic of Korea
- 折叠
摘要
Abstract
The technique of region of interest-based positron emission tomography is limited by its poor reliability and relatively few examined brain regions. In the present study, we compared brain metabolism assessed using fluorine-18-fluorodeoxyglucose positron emission tomography between 14 attention-deficit hyperactivity disorder (ADHD) patients and 15 normal controls with scoliosis at resting state by statistical parametric mapping. Glucose metabolism was decreased in the left parahippocampal gyrus, left hippocampus, left anterior cingulate gyrus, right anterior and posterior lobes of the cerebellum, left superior temporal gyrus, left insula, left medial and middle frontal gyri, right medial frontal gyrus, and left basal ganglia (putamen, amygdala, and caudate nucleus) in children with ADHD. These data suggest that children with ADHD exhibit hypometabolism in various brain regions compared to controls, indicating that ADHD symptoms are unlikely the result of abnormalities in specific areas.关键词
attention-deficit hyperactivity disorder/positron emission tomography/statistical parametric mappingKey words
attention-deficit hyperactivity disorder/positron emission tomography/statistical parametric mapping引用本文复制引用
Ji-Hoon Kim,Young-In Chung,Jung Sub Lee,In-Joo Kim,Yong-Ki Kim,Seong-Jang Kim..Voxel-based statistical analysis of regional cerebral glucose metabolism in children with attention-deficit hyperactivity disorder[J].中国神经再生研究（英文版）,2011,6(36):2850-2855,6.
