临床与实验病理学杂志2011,Vol.27Issue(12):1329-1332,4.
骨髓活检与涂片联检对诊断骨髓增生异常综合征的临床意义
Both bone marrow biopsy and smear in diagnosis of myelodysplastic syndrome
杨再林 1张勇 1徐双年 1白海雁 1杨丽莎 1黄兴琴 1蒋玲琳 1陈洁平1
作者信息
- 1. 第三军医大学西南医院血液病中心,重庆,400038
- 折叠
摘要
Abstract
Purpose To investigate the clinical significance of both bone marrow biopsy and smear methods for the diagnosis of myelo-dysplastic syndrome ( MDS ). Methods The bone marrow biopsy and aspiration were simultaneously conducted, and then histologic sections and cytologic smears prepared and observed under microscope. Results The positive rate of MDS diagnosis by biopsy was higher than that of smears. In patients with MDS diagnosed by both methods, the difference of bone marrow proliferative degree between sections and smears was statistically significant ( P <0. 05 ). The detective rate of myeloid dysplasia in sections was higher than that of smears( P < 0. 05 ), that of erythoid dysplasia in sections was lower than that of smears( P < 0. 05 ), but that of megakaryoid dysplasia was of no difference between these two methods. Conclusions In the diagnosis of MDS, both the biopsy and smears have their advantages , and the combination of these two methods will achieve much better results.关键词
骨髓增生异常综合征/骨髓涂片/骨髓活检Key words
myelodysplastic syndrome/ bone marrow smear/ bone marrow biopsy分类
医药卫生引用本文复制引用
杨再林,张勇,徐双年,白海雁,杨丽莎,黄兴琴,蒋玲琳,陈洁平..骨髓活检与涂片联检对诊断骨髓增生异常综合征的临床意义[J].临床与实验病理学杂志,2011,27(12):1329-1332,4.