中国中西医结合杂志2011，Vol.31Issue(8)：1062-1065,4.
热疗联合胸腔注射香菇多糖粉针剂治疗肺癌癌性胸水30例临床观察
Clinical Observation of Thermotherapy Combined with Thoracic Injection of Lentinan in Treatment of Cancerous Hydrothorax of Patients with Lung Cancer
李小江 1贾英杰 1陈亮 1赵成 1黄敏娜1
作者信息
- 1. 天津中医药大学第一附属医院肿瘤科,天津300193
- 折叠
摘要
Abstract
Objective To study the therapeutic effect and mechanism of thermotherapy combined with thoracic injection of lentinan in treatment of cancerous hydrothorax (CH) in patients with lung cancer. Methods Sixty lung cancer patients complicated with CH were randomly assigned to the observation group and the control group, 30 in each. CH was released by closed drainage of the thoracic cavity in all patients. Thermotherapy was given to patients in the observation group after lentinan was thoracically injected, while lentinan was thoracically injected to patients in the control group. Results The total effective rate of CH improvement was 73. 3% (22/30) in the control group and 83. 3% (25/30) in the observation group, showing insignificant difference (P>0. 05). The stability rate and the weight stability rate by Karnofsky's performance scoring in the observation group were superior to those of the control group, showing significant difference (P<0. 05). No hematological reaction, hepatic or renal damage occurred before and after treatment in both groups. Fever,thoracalgia,dyspnea,rash,nausea and vomit appeared in few patients of the two groups, showing insignificant difference (P>0. 05). CD3+, CD/, CD4VCD8+, and NK obviously increased and CD8+ decreased in the observation group after treatment, showing significant difference from those before treatment ( P < 0. 05). Compared with the control group after treatment, CD3+, CD4+, CD4VCD8+, and NK obviously increased, CD8+ increased in the observation group (P< 0. 05). Conclusion Thermotherapy combined with thoracic injection of lentinan showed better effect in treatment of CH in patients with lung cancer. No obvious adverse reaction was seen.关键词
热疗/香菇多糖/癌性胸水Key words
thermotherapy/ lentinan/ cancerous hydrothorax引用本文复制引用
李小江,贾英杰,陈亮,赵成,黄敏娜..热疗联合胸腔注射香菇多糖粉针剂治疗肺癌癌性胸水30例临床观察[J].中国中西医结合杂志,2011,31(8):1062-1065,4.
