摘要
Abstract
Objective To explore the distribution features of Chinese medicine syndrome types in immu-noglobin A (IgA) nephropathy patients complicated with hypertension and its correlation with main prognostic indicators of hypertension classification and chronic kidney disease (CKD) staging, thus providing the diagnostic standards of Chinese medicine syndrome types and reliance for accurate syndrome differentiated medication. Methods By on-the-spot survey, the Chinese medicine syndrome and laboratory testing data of 154 IgA nephropathy patients complicated with hypertension confirmed by the pathology of kidneys were collected to analyze the distribution of Chinese medicine syndrome types, its correlation with hypertension classification and CKD staging. Results Asthenia was the most common syndrome in the 154 patients (146 cases, 94. 81%), covering Pi-Shen deficiency syndrome (58, 37. 66%), Shen qi-yin deficiency syndrome (48, 31.17%), and Gan-Shen yin deficiency syndrome (40, 25.97%). Of them, asthenia accompanied by sthenia was seen in 80 cases (54. 79%) and pure sthenia in 8 cases (5.2%). Shen qi-yin deficiency syndrome and Gan-Shen yin deficiency syndrome were mostly seen in hypertension Ⅲ, while Pi-Shen deficiency syndrome was mostly seen in hypertension Ⅰ. Pi-Shen deficiency syndrome was mostly seen in CKD stage 4, Shen qi-yin deficiency syndrome mostly seen in CKD stage 1 -2, and Gan-Shen yin deficiency syndrome mainly distributed in CKD stage 1 -3. No obvious correlation was seen between Chinese medicine syndrome types and 24-h urine protein quantitation. Conclusions Pi-Shen deficiency syndrome, Shen qi-yin deficiency syndrome, and Gan-Shen yin deficiency syndrome were main Chinese medicine syndrome types in IgA nephropathy patients complicated with hypertension. Asthenia accompanied by sthenia was mostly seen. Pi-Shen deficiency syndrome was mostly seen in hypertension Ⅰ. Shen qi-yin deficiency syndrome and Gan-Shen yin deficiency syndrome were mostly seen in hypertension Ⅲ, Shen qi-yin deficiency syndrome mostly seen in CKD stage 1 -2, and Gan-Shen yin deficiency syndrome mainly distributed in CKD stage 1 -3. Pi-Shen deficiency syndrome was mostly seen in CKD stage 4 patients.关键词
IgA肾病合并高血压/中医证型/相关因素分析Key words
immunoglobin A nephropathy complicated with hypertension/ Chinese medicine syndrome type/ analysis of correlation factors
