动物营养学报2011，Vol.23Issue(10)：1647-1650,4.DOI:10.3969/j.issn.1006-267x.2011.10.001
microRNA在骨骼肌发育中的功能及其表达的营养调控
MicroRNA: Functions in Skeletal Muscle Development and Nutritional Regulations on Its Expression
摘要
Abstract
MicroRNAs (miRNAs)are a class of small non-coding RNA that act as regulators of gene expression in eucaryota. They negatively regulate gene expression by translational suppression and target mRNA degradation, and are closely related to skeletal muscle development and muscular diseases. Nutrition can regulate expression of miRNA and its target genes, which may bring a new research direction for mechanisms of nutrients. This paper mainly reviews research advances in structure and mechanism of miRNA, skeletal muscle miRNA expression profiling in different kinds of animals, miRNA regulation of skeletal muscle development, relationship between miRNA and skeletal diseases, as well as nutritional regulation of miRNA expression.关键词
microRNA/骨骼肌发育/营养调控Key words
microRNA/ skeletal muscle development/ nutritional regulation分类
农业科技引用本文复制引用
黄志清,陈小玲,余冰,毛湘冰,陈代文..microRNA在骨骼肌发育中的功能及其表达的营养调控[J].动物营养学报,2011,23(10):1647-1650,4.基金项目
国家自然科学基金(30972119) （30972119）
四川省教育厅资助科研项目(00924800) （00924800）
